Home Site map Contacts



Droxinostat is a novel HDAC inhibitor. It selectively inhibits HDAC3, HDAC6, and HDAC8 with an IC50 of 16.9, 2.47 and 1.46 µM/L, respectively, but did not inhibit HDAC1, HDAC2, HDAC4, HDAC5, HDAC7, HDAC9, and HDAC10, with an IC50 of >20 µM/L.

Synonyms: 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
Technical Data: Molecular Weight - 243.69; Molecular formula - C11H14ClNO3; CAS No - 99873-43-5

Ordering Information: Product Number - EC-000.2480; Price and Availability: Inquire This product is also available to buy in bulk quantities.

Related Products: Suberoylanilide Hydroxamic Acid; MS-275 (Entinostat); CI-994 (Tacedinaline); BML-210; M344; MGCD0103 (Mocetinostat); PXD101 (Belinostat); LBH-589 (Panobinostat); Tubastatin A; Scriptaid; NSC 3852; NCH 51; HNHA; BML-281; CBHA; Salermide; Pimelic Diphenylamide; ITF2357 (Givinostat); PCI-24781; APHA Compound 8; SB939.

1. Wood TE, Dalili S, Simpson CD, et al. Selective inhibition of histone deacetylases sensitizes malignant cells to death receptor ligands. Mol Cancer Ther. 2010 Jan;9(1):246-56.

Home  |  About Company  |  Contract Synthesis  |  Cheminformatics Services  |  Info for Chemists  |  Contacts  |  FAQ  |  Site Map

© 2004-2016 Exclusive Chemistry Ltd. All rights reserved.